Publikationen von Mitarbeitern der Klinik
2024
Brinkers M, Pfau G, Strang CM, Lodes U, Barth U, Meyer F, Halloul Z
Moderne medikamentöse Schmerztherapie in der Gefäßmedizin – was der Gefäßchirurg dazu wissen sollte anhand einer einrichtungsspezifischen „Standard Operating Procedure“ (SOP)
Gefässchirurgie (2024) https://doi.org/10.1007/s00772-024-01158-w
Brinkers M, Beyer l, Niemier K
Funktionelle Schmerzsyndrome im Rahmen von funktionellen neurologischen Störungen Teil 2: Hysterie als Konstrukt entbehrlich?
Manuelle Medizin (2024). https://doi.org/10.1007/s00337-024-01092-8
Brinkers M, Pfau G, Thielmann B, Böckelmann I
Cybernetic Principles in Psychophysiology: Their Significance and Conclusions for Palliative Care (Review)
Healthcare 2024, 12, 1510. https://doi.org/10.3390/healthcare12151510
Niemier K, Vitt E, Brinkers M
Das Fibromyalgiesyndrom aus funktioneller Sicht – ein typisches Beispiel für eine Funktionserkrankung
Manuelle Medizin (2024) https://doi.org/10.1007/s00337-024-01064-y
Brinkers M, Niemier K
Funktionelle Schmerzsyndrome im Rahmen von funktionellen neurologischen Störungen Teil 1: Funktionelle Störungen als Konversionsstörungen?
Manuelle Medizin (2024). https://doi.org/10.1007/s00337-024-01047-z
Danyeli L, Zümrütl D, Colic L, Opel N, Refisch A, Blekic N, Macharadze T, Kretzschmar M, Munk M, Gaser Ch, Speck O, Walter M, Li M.
Cortical thickness of the posterior cingulate cortex is associated with the ketamine-induced altered sense of self: An ultra-high field MRI study.
Journal of Psychiatric Research, Feb 2024 DOI: 10.1016/j.jpsychires.2024.02.019.
2023
Kowark A, Keszei AP, Schneider G, Pilge S, Schneider F, Obert DP, Georgii MT, Heim M, Rossaint R, Ziemann S, van Waesberghe J, Czaplik M, Pühringer FK, Minarski C, May V, Malisi T, Drexler B, Ring CM, Engler P, Tilly R, Bischoff P, Frey U, Wittmann M, Soehle M, Saller T, Kienbaum P, Kretzschmar M, Coburn M; I-PROMOTE Study Group.
Preoperative Midazolam and Patient-Centered Outcomes of Older Patients: The I-PROMOTE Randomized Clinical Trial.
JAMA Surg. 2023 Dec 20. doi: 10.1001/jamasurg.2023.6479. Epub ahead of print.
Brinkers M.: Bio-psycho-soziale Aspekte der Bewegungsfunktion. Kap.3; S. 69-75.
Liefring V, Brinkers M.: Besonderheiten der Diagnostik und Therapie der Funktionskrankheiten. Kap 9; S. 153-160.
Brinkers M.: Präsenz der Psyche. Kapitel 12.4; S. 206-213
Buchkapitel in: Beyer L, Liefring V, Niemier K, Seidel E. Funktiosnmedizin. München: Kiener 2023; ISBN 978-3-948442-24-8
Brinkers M, Istel M, Kretzschmar M, Pfau G, Meyer F
Status of inpatient pain therapy using the example of a general and abdominal surgery normal ward – a prospective questionnaire study to review a pain therapy algorithm (“real-world data”)
Innovative Surgical Sciences, vol. 8, no. 2, 2023, pp. 73-82. https://doi.org/10.1515/iss-2023-0016
Brinkers M, Ulrich P, Vogt A, Kretzschmar M, Pfau G
Hysterie – ein obsoleter Begriff auch bei der Leistungsbeurteilung im Rentenverfahren von Patienten mit chronischen Schmerzen? Eine Zusammenschau von 50 Sozialgerichtsgutachten
NEUROL NEUROCHIR PSYCHIATR 2023; 24 (3)
Sen ZD, Chand T, Danyeli LV, Kumar VJ, Colic L, Li M, Yemisken M, Javaheripour N, Refisch A, Opel N, Macharadze T, Kretzschmar M, Ozkan E, Deliano M, Walter M.
The effect of ketamine on affective modulation of the startle reflex and its resting-state brain correlates.
Sci Rep. 2023 Aug 16;13(1):13323. doi: 10.1038/s41598-023-40099-4.
Kuzmin B, Movsisyan A, Praetsch F, Schilling T, Lux A, Fadel M, Azizzadeh F, Crackau J, Keyser O, Awad G, Hachenberg T, Wippermann J, Scherner M.
Outcomes of patients with coronavirus disease versus other lung infections requiring venovenous extracorporeal membrane oxygenation.
Heliyon. 2023 Jun;9(6):e17441. doi: 10.1016/j.heliyon.2023.e17441
Brinkers M, Pfau G, Meyer
Tumorschmerzen akut vs. chronisch vs. Nichttumorschmezen - Unterschiede und Gemeinsamkeiten
JATROS Hämatologie & Onkologie 04/2023
Brinkers M, Pfau G
ICD-11: Beseitigung aller Probleme bei nichterklärbaren somatisch wahrgenommenen Symptomen?
Manuelle Medizin 2023 https://doi.org/10.1007/s00337-023-00980-9
Brinkers M, Galow AM, Pfau G
Psychiatrie für Manualmediziner
Manuelle Medizin 2023 https://doi.org/10.1007/s00337-023-00978-3
Brinkers M, Pfau G, Niemier K
Fehlende funktionelle Untersuchung bei Patienten mit chronischen Schmerzen – und nun?
Manuelle Medizin 2023 https://doi.org/10.1007/s00337-023-00956-9
Pain Med. 2023 Jan 20; pnad004. doi: 10.1093/pm/pnad004
Brinkers M, Diefenbacher A, Burian R, Kretzschmar M, Pfau G
Telling the Difference between a Histrionic Personality Disorder and the Manic Phase of a Bipolar Disorder in a Pain Clinic, or who is at Risk for Suicide?-A Case Series with Seven Patients
Ann Case Report. 8: 1139. https://doi.org/10.29011/2574-7754.101139
2022
Dombrowsky S, Pfau G, Kretzschmar M, Meyer F, Brinkers M
Depressionen bei somatischen Krankheiten am Beispiel der ischämischen Herzkrankheit und ausgewählter Tumorerkrankungen mit beträchtlicher Relevanz für Morbidität und Letalität
J NEUROL NEUROCHIR PSYCHIATR 2022; 23 (4); https://www.kup.at/journals/summary/15289.html
Brinkers M, Pfau G, Voigt A, Brodowski S, Meyer F
Keine Interdisziplinarität ohne Interprofessionalität in der Schmerztherapie
intensiv 2022; 30: 294–301; DOI https://doi.org/10.1055/a-1926-1517
Brinkers M, Voigt A, Pfau G
Sexueller Missbrauch bei Patientinnen mit chronischer Schmerzsymptomatik
Geburtsh Frauenheilk 2022; 82: 901-908 DOI https://doi.org/10.1055/a-1676-8537
Brinkers M, Niemier K.
Schmerz mit Funktion - psychosoziale Stabilisierung durch Schmerz
Manuelle Medizin (2022) https://doi.org/10.1007/s00337-022-00865-3
Breitling C, Kretzschmar M
Ultraschallgestützte Regionalanästhesie in der Thoraxchirurgie
AINS 2022; 57(06): 417 - 427 https://doi.org/10.1055/a-1494-4387
Vitt, E.M. Niemier K., Brinkers M.
Diagnostik und Therapie als Mitursache für die Chronifizierung von Schmerzerkrankungen des Bewegungssystems - Iatrogenisierung im klinischen Alltag: Eine Fallvorstellung
Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin https://doi.org/10.1055/a-1839-9109
2021
Th Schilling, A Bergmann
Chapter 7 - Modulating the Pulmonary Circulation: Nitric Oxide and Beyond
in Cohen's Comprehensive Thoracic Anesthesia
Elsevier 2021, ISBN 978-0-323-71301-6
Th Hachenberg, T Loop
Chapter 27 - Postthoracotomy Complications
in Cohen's Comprehensive Thoracic Anesthesia
Elsevier 2021, ISBN 978-0-323-71301-6
A Kozian, M Kretzschmar
Chapter 33 - Thoracic Trauma
in Cohen's Comprehensive Thoracic Anesthesia
Elsevier 2021, ISBN 978-0-323-71301-6
Kretzschmar M, Baumgardner JE, Kozian A, Hachenberg T, Schilling T, Hedenstierna G, Larsson A.
Arterial and Mixed Venous Kinetics of Desflurane and Sevoflurane, Administered Simultaneously, at Three Different Global Ventilation to Perfusion Ratios in Piglets with Normal Lungs. Anesthesiology. 2021 Nov 3. doi: 10.1097/ALN.0000000000004007. Epub ahead of print.
Baumgardner JE, Kretzschmar M, Kozian A, Hachenberg T, Schilling T, Larsson A, Hedenstierna G.
Effect of Global Ventilation to Perfusion Ratio, for Normal Lungs, on Desflurane and Sevoflurane Elimination Kinetics.
Anesthesiology. 2021 Nov 3. doi: 10.1097/ALN.0000000000004008. Epub ahead of print.
Brinkers M, Pfau G, Ritz W, Meyer F, Kretzschmar M.
What does low psychological distress mean in patients with no mental disorders and different pains of the musculoskeletal system?
Scandinavian Journal of Pain. 2021 https://doi.org/10.1515/sjpain-2021-0010
Brinkers M., Lux A., Pfau G., Schneemilch C.
Charakteristik und Prävalenz schmerzhafter Zönästhesien in einer Schmerzambulanz
Der Schmerz, (), 1-7, https://www.doi.org/10.1007/s00482-021-00592-z
Niklas C. , Fakundini B., Popov A., Walles Th.
Special Anesthesiologic Considerations in Robot-Assisted Thoracic Surgery
Current Anesthesiology Reports (2021), https://doi.org/10.1007/s40140-021-00471-4
Brinkers M., Pfau G. , Toepffer A.-M., Meyer F., Kretzschmar M.
The Incidence of Mental Disorders Increases over Time in Patients with Cancer Pain: Data from a Retrospective Cohort Study
Pain Research and Management, vol. 2021, 7 pages, 2021. https://doi.org/10.1155/2021/5515629
Brinkers, M., Wander R, Kretzschmar M, Rothkötter H-J, Pfau G
Erhöhen viszeralchirurgische Eingriffe das Risiko an Rückenschmerzen zu erkranken?
Deutsche Zeitschrift für Akupunktur (April, 2021) DOI 10.1007/s42212-021-00387-4
2020
Brinkers M, Pfau G
Der Begriff „Funktion/funktionell“ in der manuellen Medizin und Psychosomatik bzw. inneren Medizin - Gemeinsamkeiten und Unterschiede
Manuelle Medizin (2020);ePub 2020 Aug 12; https://doi.org/10.1007/s00337-020-00723-0
Vogt S, Schreiber S, Pfau G, Kollewe K, Heinze HJ, Dengler R, Petri S, Vielhaber S, Brinkers M.
Dyspnea as a Fatigue-Promoting Factor in ALS and the Role of Objective Indicators of Respiratory Impairment.
J Pain Symptom Manage. 2020 Aug;60(2):430-438.e1. doi: 10.1016/j.jpainsymman.2020.02.021. Epub 2020 Mar 5.
Keilhoff G, Nguyen Thi TM, Esser T, Ebmeyer U.
Relative Resilience of Cerebellar Purkinje Cells in a Cardiac Arrest/Resuscitation Rat Model.
Neurocrit Care. 2020 Jun;32(3):775-789. doi: 10.1007/s12028-019-00799-0.
Bergmann A, Schilling T, Perchiazzi G, Kretzschmar M, Hedenstierna G, Hachenberg T, Larsson A.
Effect of remote ischemic preconditioning on exhaled nitric oxide concentration in piglets during and after one-lung ventilation.
Respir Physiol Neurobiol. 2020 May;276:103426. doi: 10.1016/j.resp.2020.103426. Epub 2020 Feb 28.
Keilhoff G, Titze M, Rathert H, Lucas B, Esser T, Ebmeyer U.
Normoxic post-ROSC ventilation delays hippocampal CA1 neurodegeneration in a rat cardiac arrest model, but does not prevent it.
Exp Brain Res. 2020 Apr;238(4):807-824. doi: 10.1007/s00221-020-05746-6. Epub 2020 Mar 3.
Schneider F, Schulz CM, May M, Schneider G, Jacob M, Mutlak H, Pawlik M, Zoller M, Kretzschmar M, Koch C, Kees MG, Burger M, Lebentrau S, Novotny A, Hübler M, Koch T, Heim M.
[Is the discipline associated with self-confidence in handling rational antibiotic prescription? : Results from the MR2 study in German hospitals].
Anaesthesist. 2020 Mar;69(3):162-169. doi: 10.1007/s00101-020-00736-3. Epub 2020 Feb 13.
Schneider F, Schulz CM, May M, Schneider G, Ernst C, Jacob M, Zacharowski K, Hachenberg T, Schmidt M, Kretzschmar M, Graf B, Kees MG, Pawlik M, Sander M, Koch C, Zoller M, Heim M.
The association of the anesthesiologist's academic and educational status with self-confidence, self-rated knowledge and objective knowledge in rational antibiotic application.
BMC Res Notes. 2020 Mar 18;13(1):161. doi: 10.1186/s13104-020-05010-8.
Greiner F, Slagman A, Stallmann C, March S, Pollmanns J, Dröge P, Günster C, Rosenbusch ML, Heuer J, Drösler SE, Walcher F, Brammen D.
[Routine Data from Emergency Departments: Varying Documentation Standards, Billing Modalities and Data Custodians at an Identical Unit of Care].
Gesundheitswesen. 2020 Mar;82(S 01):S72-S82. doi: 10.1055/a-0996-8371. Epub 2019 Oct 9.
Keilhoff G, Ebmeyer U.
Commentary to: "Therapeutic hypothermia attenuates paraplegia and neuronal damage in the lumbar spinal cord in a rat model of asphyxial cardiac arrest" by Lee et al., J Therm Biol 83 (2019) 1-7.
J Therm Biol. 2020 Jan;87:102454. doi: 10.1016/j.jtherbio.2019.102454. Epub 2019 Nov 18.
Bergmann A, Jovanovska E, Schilling T, Hedenstierna G, Föllner S, Schreiber J, Hachenberg T.
Early and late effects of remote ischemic preconditioning on spirometry and gas exchange in healthy volunteers.
Respir Physiol Neurobiol. 2020 Jan;271:103287. doi: 10.1016/j.resp.2019.103287. Epub 2019 Sep 5.
Vogt S, Schreiber S, Pfau G, Kollewe K, Heinze HJ, Dengler R, Petri S, Vielhaber S, Brinkers M
Dyspnea as a fatigue-promoting factor in ALS and the role of objective indicators of respiratory impairment
J Pain Symptom Manage 2020, Mar 4, pii: S0885-3924(20)30124-X. doi: 10.1016/j.jpainsymman.2020.02.021
2019
F. Schneider, C. M. Schulz, M. May, M. Pawlik, M. Hübler, J. Soukup, C. Ernst, G. Schneider, M. Jacob, F. Brettner, M. G. Kees, B. Graf, M. Kretzschmar, T. Hachenberg ,M. Schmidt, C. Koch , M. Sander, M. Zoller, T. Koch, S. Brookman-May, M. Heim, MR2-Studiengruppe
Unterscheiden sich Anästhesisten an Universitätskliniken bezüglich ihres Selbstvertrauens und Wissens über rationale Antibiotikaverordnung von ihren nicht-universitär tätigen Kollegen? Ergebnisse einer Fragebogenstudie an deutschen Krankenhäusern.
Anästh Intensivmed 2019;60:468–478. DOI: 10.19224/ai2019.468
Kowark A, Rossaint R, Keszei AP, Bischoff P, Czaplik M, Drexler B, Kienbaum P, Kretzschmar M, Rex C, Saller T, Schneider G, Soehle M, Coburn M; I-PROMOTE study group.
Impact of PReOperative Midazolam on OuTcome of Elderly patients (I-PROMOTE): study protocol for a multicentre randomised controlled trial.
Trials. 2019 Jul 15;20(1):430. doi: 10.1186/s13063-019-3512-3.
Kiss T, Wittenstein J, Becker C, Birr K, Cinnella G, Cohen E, El Tahan MR, Falcão LF, Gregoretti C, Granell M, Hachenberg T, Hollmann MW, Jankovic R, Karzai W, Krassler J, Loop T, Licker MJ, Marczin N, Mills GH, Murrell MT, Neskovic V, Nisnevitch-Savarese Z, et al.
Correction to: Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (PROTHOR): study protocol for a randomized controlled trial.
Trials. 2019 May 8;20(1):259. doi: 10.1186/s13063-019-3371-y.
Brinkers M, Pfau G, Schneemilch C.
[Aspects of liaison psychiatry care of patients in a university pain clinic].
Schmerz. 2018 Apr;32(2):115-120. doi: 10.1007/s00482-018-0267-9. German.
Heim M, Schneider F, Mutlak H, Schulz CM, Hachenberg T, Zoller M, Soukup J, Pawlik M, Schön J, Kees M, Hübler M, Sander M, Ernst C, Jacob M, May M; MR2 Study Group.. Rational application of antibiotics-The influence of anaesthetists' gender on self-confidence and knowledge.
Acta Anaesthesiol Scand. 2019 Apr 22. doi: 10.1111/aas.13376.
Kiss T, Wittenstein J, Becker C, Birr K, Cinnella G, Cohen E, El Tahan MR, Falcão LF, Gregoretti C, Granell M, Hachenberg T, Hollmann MW, Jankovic R, Karzai W, Krassler J, Loop T, Licker MJ, Marczin N, Mills GH, Murrell MT, Neskovic V, Nisnevitch-Savarese Z, et al.
Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (PROTHOR): study protocol for a randomized controlled trial.
Trials. 2019 Apr 11;20(1):213. doi: 10.1186/s13063-019-3208-8. Erratum in: Trials. 2019 May 8;20(1):259.
Lucas B, Brammen D, Schirrmeister W, Aleyt J, Kulla M, Röhrig R, Walcher F.
[Requirements for a sustainable standardization and digitalization in clinical emergency and acute medicine].
Unfallchirurg. 2019 Mar;122(3):243-246. doi: 10.1007/s00113-019-0603-2. German.
Colic L, McDonnell C, Li M, Woelfer M, Liebe T, Kretzschmar M, Speck O, Schott BH, Bianchi M, Walter M.
Neuronal glutamatergic changes and peripheral markers of cytoskeleton dynamics change synchronically 24h after sub-anaesthetic dose of ketamine in healthy subjects.
Behav Brain Res. 2019 Feb 1;359:312-319. doi: 10.1016/j.bbr.2018.10.021. Epub 2018 Oct 17.
M. May, T. Hachenberg, S. Brookman-May, C. Ernst, B. Zwißler, C. Glückstein, M. Heim, J. Soukup, H. Mutlak, M. Pawlik, J. Schön, M. Kees, M. Kretzschmar, A. Freitag, M. Hübler, F. Breitner, M. Schmidt, G. Boeden, C. Schulz, G. Badelt, C. Koch, M. Sander · B. Graf, M. Zoller, K. Zacharowski, M. Jacob, MR2-Studiengruppe
Unterschiede von Kenntnissen und Selbsteinschätzung der Ärztinnen und Ärzte in Weiterbildung im Vergleich zu Fachärztinnen und Fachärzten der Anästhesiologie zu Fragen der Multiresistenz bakterieller Erreger und einer rationalen Antibiotikaverordnung
Anästh Intensivmed 2019;60:150–163. DOI: 10.19224/ai2019.150
Bergmann A, Schilling T, Hedenstierna G, Ahlgren K, Larsson A, Kretzschmar M, Kozian A, Hachenberg T.
Pulmonary effects of remote ischemic preconditioning in a porcine model of ventilation-induced lung injury.
Respir Physiol Neurobiol. 2019 Jan;259:111-118. doi: 10.1016/j.resp.2018.08.009.
2018
Kozian A, Schilling T
[Asthmatic attack].
MMW Fortschr Med. 2018 Dec;160(21-22):50-51. doi: 10.1007/s15006-018-1236-z.
Bergmann A, Breitling C, Hedenstierna G, Larsson A, Kretzschmar M, Kozian A, Hachenberg T, Schilling T.
Data on the effects of remote ischemic preconditioning in the lungs after one-lung ventilation.
Data Brief. 2018 Oct 4;21:441-448. doi: 10.1016/j.dib.2018.09.085.
Kowark A, Adam C, Ahrens J, Bajbouj M, Bollheimer C, Borowski M, Dodel R, Dolch M, Hachenberg T, Henzler D, Hildebrand F, Hilgers RD, Hoeft A, Isfort S, Kienbaum P, Knobe M, Knuefermann P, Kranke P, Laufenberg-Feldmann R, Nau C, Neuman MD, Olotu C, et al.
Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia.
BMJ Open. 2018 Oct 18;8(10):e023609. doi: 10.1136/bmjopen-2018-023609.
Brinkers M, Rumpelt P, Lux A, Kretzschmar M, Pfau G
Psychiatric Disorders in Complex Regional Pain Syndrome (CRPS): The Role of the Consultation-Liaison Psychiatrist
Pain Research and Management, vol. 2018, Article ID 2894360, 8 pages, 2018. doi: 10.1155/2018/2894360.
Liebe T, Li M, Colic L, Munk MHJ, Sweeney-Reed CM, Woelfer M, Kretzschmar MA, Steiner J, von Düring F, Behnisch G, Schott BH, Walter M.
Ketamine influences the locus coeruleus norepinephrine network, with a dependency on norepinephrine transporter genotype - a placebo controlled fMRI study.
Neuroimage Clin. 2018 Sep 4;20:715-723. doi: 10.1016/j.nicl.2018.09.001.
Bergmann A, Schilling T, Hedenstierna G, Ahlgren K, Larsson A, Kretzschmar M, Kozian A, Hachenberg T.
Pulmonary effects of remote ischemic preconditioning in a porcine model of ventilation-induced lung injury.
Respir Physiol Neurobiol. 2018 Aug 31. pii: S1569-9048(18)30231-3. doi: 10.1016/j.resp.2018.08.009
Brammen D, Greiner F, Dormann H, Mach C, Wrede C, Ballaschk A, Stewart D, Walker S, Oesterling C, Kulla M.
Lessons learned in applying the International Society for Pharmacoeconomics and Outcomes Research methodology to translating Canadian Emergency Department Information System Presenting Complaints List into German.
Eur J Emerg Med. 2018 Aug;25(4):295-299. doi: 10.1097/MEJ.0000000000000450.
Kampe S, Wendland M, Welter S, Aigner C, Hachenberg T, Ebmeyer U, Weinreich G.
Independent Predictors for Higher Postoperative Pain Intensity During Recovery After Open Thoracic Surgery: A Retrospective Analysis in 621 Patients.
Pain Med. 2018 Aug 1;19(8):1667-1673. doi: 10.1093/pm/pnx238.
Colic L, Woelfer M, Colic M, Leutritz AL, Liebe T, Fensky L, Sen ZD, Li M, Hoffmann J, Kretzschmar MA, Isermann B, Walter M.
Delayed increase of thrombocyte levels after a single sub-anesthetic dose of ketamine - A randomized trial.
Eur Neuropsychopharmacol. 2018 Jun;28(6):701-709. doi: 10.1016/j.euroneuro.2018.03.014. Epub 2018 Apr 24.
Hörster AC, Kulla M, Brammen D, Lefering R.
[Potential for the survey of quality indicators based on a national emergency department registry : A systematic literature search].
Med Klin Intensivmed Notfmed. 2018 Jun;113(5):409-417. doi: 10.1007/s00063-016-0180-x. Epub 2016 Jun 29.
Meybohm P, Kohlhaas M, Stoppe C, ..., Schilling T, ..., Zacharowski K; RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study Collaborators.
RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow-Up.
J Am Heart Assoc. 2018 Mar 26;7(7). pii: e008077. doi: 10.1161/JAHA.117.008077.
Brammen D, Eggert P, Lucas B, Heermann-Langford L, McClay JC.
Comparing the German Emergency Department Medical Record with the US HL7 Data Elements for Emergency Department Systems.
Stud Health Technol Inform. 2018;247:216-220.
Greiner F, Brammen D, Kulla M, Walcher F, Erdmann B.
[Standardized collection of presenting complaints in the emergency room : Integration of coded presenting complaints into the electronic medical record system of an emergency department and their value for health care research].
Med Klin Intensivmed Notfmed. 2018 Mar;113(2):115-123. doi: 10.1007/s00063-017-0286-9. Epub 2017 Apr 26.
Serpa Neto A, Juffermans NP, Hemmes SNT, ..., Kozian A, ..., Schilling T, ..., Schultz MJ; PROVE Network Investigators.
Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis.
Ann Transl Med. 2018 Jan;6(2):23. doi: 10.21037/atm.2018.01.16.
Brinkers, M. & Pfau, G.
Die Psyche beginnt im Soma
Manuelle Medizin (2018); https://doi.org/10.1007/s00337
Brinkers, M., Pfau, G. & Schneemilch, C.
Aspekte einer liaisonpsychiatrischen Betreuung von Patienten einer universitären Schmerzambulanz
Schmerz (2018). https://doi.org/10.1007/s00482-018-0267-9
2017
M.Brinkers,·B.Balkaner,·G.Pfau
Histrionische Persönlichkeitsstörung und Schmerz – wenn eine psychische Störung operiert wird
Manuelle Medizin (2017). DOI: 10.1007/s00337-017-0307-z
Kretzschmar M, Kozian A, Baumgardner JE, Borges JB, Hedenstierna G, Larsson A, Hachenberg T, Schilling T.
Effect of Bronchoconstriction-induced Ventilation-Perfusion Mismatch on Uptake and Elimination of Isoflurane and Desflurane.
Anesthesiology. 2017 2017 Nov;127(5):800-812. doi: 10.1097/ALN.0000000000001847.
Nagy P, Antony C, Hegedüs B, Kampe S, Ploenes T, Aigner C, Welter S.
Same-day Routine Chest-X Ray After Thoracic Surgery is Not Necessary!
Zentralbl Chir. 2018 Feb;143(1):96-101. doi: 10.1055/s-0043-117174. Epub 2017 Sep 13.
Wäsche A, Kandulski A, Malfertheiner P, Riedel S, Zardo P, Hachenberg T, Schreiber J.
Impact of thoracic surgery on esophageal motor function-Evaluation by high resolution manometry.
J Thorac Dis. 2017 Jun;9(6):1557-1564. doi: 10.21037/jtd.2017.05.43.
Ozan Akça, Lorenzo Ball, F. Javier Belda, Peter Biro, Andrea Cortegiani, Arieh Eden, Carlos Ferrando, Luciano Gattinoni, Zeev Goldik, Cesare Gregoretti, Thomas Hachenberg, Göran Hedenstierna, Harriet W. Hopf, Thomas K. Hunt, Paolo Pelosi, Motaz Qadan, Daniel I. Sessler, Marina Soro, Mert Şentürk.
WHO Needs High FIO2?
Turk J Anaesthesiol Reanim. 2017; 45(4): 181-192; DOI: 10.5152/TJAR.2017.250701
T. Liebe,..., M. Kretzschmar, C. Sweeney-Reed, G. Behnisch, B. Schott, M. Walter
Factors influencing the cardiovascular response to sub-anesthetic ketamine – a randomized, placebo controlled trial
International Journal of Neuropsychopharmacology 2017 Nov 1;20(11):909-918.; DOI: 10.1093/ijnp/pyx055
Brinkers M., Pfau G., Lodes U., Jacob D., Meyer F.
CME-Artikel: Medikamentöse Schmerztherapie - Wissen des Chirurgen.
Passion Chirurgie. 2017 März; 7(03)
Hansen M, Hachenberg T.
[Thoracic Trauma - Prehospital Treatment].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2017 Jun;52(6):408-421. doi: 10.1055/s-0042-118056. Epub 2017 Jun 14. German.
Kozian A, Bergmann A, Hachenberg T, Schilling T
Der Patient mit Thoraxtrauma: anästhesiologisches Management - Anesthetic Management in Thoracic Trauma Patients
Anästhesiol Intensivmed Notfallmed Schmerzther 2017; 52(06): 422-435; DOI: 10.1055/s-0042-118055
Greiner F, Brammen D, Kulla M, Walcher F, Erdmann B.
[Standardized collection of presenting complaints in the emergency room : Integration of coded presenting complaints into the electronic medical record system of an emergency department and their value for health care research].
Med Klin Intensivmed Notfmed. 2017 Apr 26. doi: 10.1007/s00063-017-0286-9. [Epub ahead of print] German.
Hachenberg T, Kols K.
OP-Vorbereitung: Vertrauen ist gut, Kontrolle ist besser.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2017 Mar;52(3):228-230. doi: 10.1055/s-0043-102641. Epub 2017 Mar 16. German. No abstract available.
Jauch J, Pfau G, Kretzschmar M, Bergmann A, Schilling T, Brinkers M
The Conversion from Continuous Sufentanil Infusion to Oral Retarded Opioid Medication: Beware of the Equi-Analgesic Opioid Ratios – A Case Series
J Anest & Inten Care Med. Vol. 2 (1) -March 2017
Darr C, Cheufou D, Weinreich G, Hachenberg T, Aigner C, Kampe S.
Robotic thoracic surgery results in shorter hospital stay and lower postoperative pain compared to open thoracotomy: a matched pairs analysis.
Surg Endosc. 2017 Mar 8. [Epub ahead of print]
2016
Zardo P, Kreft T, Hachenberg T.
Airway Management via Laryngeal Mask in Laryngotracheal Resection.
Thorac Cardiovasc Surg Rep. 2016 Dec;5(1):1-3.
Esser T, Keilhoff G, Ebmeyer U.
Anesthesia specific differences in a cardio-pulmonary resuscitation rat model; halothane versus sevoflurane.
Brain Res. 2016 Dec 1;1652:144-150.
Kampe S, Geismann B, Weinreich G, Stamatis G, Ebmeyer U, Gerbershagen HJ.
The Influence of Type of Anesthesia, Perioperative Pain, and Preoperative Health Status on Chronic Pain Six Months After Thoracotomy-A Prospective Cohort Study.
Pain Med. 2016 Sep 20
T. Hachenberg, J. Neu, K. Kols, W. Schaffartzik
Medizinische und juristische Bewertung von schweren Behandlungsfehlern in Anästhesiologie, Intensivtherapie und Notfallmedizin
Anästh Intensivmed 2016;57:530-540
Kampe S, Rocha M, Darwiche K, Ebmeyer U, Georgios S.
Suffiziente High-Frequency-Jet-Ventilation über 2,5 h -Atemwegsmanagement bei OP einer ausgedehnten ösophagotrachealen Fistel und Tracheateilresektion
Anästhesiol Intensivmed Notfallmed Schmerzther 2016; 51(06): 368-371
Asthma bronchiale - Bedeutung in der klinischen Anästhesie und Notfallmedizin
Anästhesiol Intensivmed Notfallmed Schmerzther 2016; 51(06): 390-391
Kozian A, Schilling Th, Hachenberg Th.
Asthma bronchiale - Anästhesiologisches Management
Anästhesiol Intensivmed Notfallmed Schmerzther 2016; 51(06): 402-409
Brinkers M, Pfau G, Lux A, Pfau G, Schneemilch C, Meyer F, Grond S
Stationäre medikamentöse Schmerztherapie bei Tumorpatienten: Effekte einer manualisierten Leitlinie für den Konsildienst eines Universitätsklinikums
Dtsch Med Wochenschr 2016; 141: e39-46
Brammen D, Rickert V, Esser T, Prätsch F, Röhrig R, Hachenberg T, Ebmeyer U.
Identifikation und ökonomische Bewertung von anästhesiologischen Nebendiagnosen auf Basis von intraoperativen Medikamentengaben
Anaesthesist. 2016 May 25. [Epub ahead of print]
Brinkers M, Pfau G, Meyer F, Kretzschmar M, Ebmeyer U, Schilling Th.
The combination of pain and aggression – two impressive and representative case reports
J Anesth Surg 2016; 3: doi: 10.15436/2377-1364.16.032
Neto AS, ..., Kozian A,..., Schilling T,..., Schultz MJ; PROVE Network Investigators.
Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data.
Lancet Respir Med. 2016 Mar 3. doi: 10.1016/S2213-2600(16)00057-6. [Epub ahead of print]
M. Brinkers, G. Pfau, T. Schilling, F. Meyer
Risiken perioperativer Benzodiazepin-Abhängigkeit beim alten Menschen – was der Chirurg hierzu wissen sollte.
Zentralbl Chir 2016; 141(01): 75-81
Kretzschmar MA, Hachenberg T.
Thoracic anaesthesia 2016.
Curr Opin Anaesthesiol. 2016 Feb;29(1):1. doi: 10.1097/ACO.0000000000000289.
Haverkamp W, Hachenberg T.
Post-thoracotomy dysrhythmia.
Curr Opin Anaesthesiol. 2016 Feb;29(1):26-33. doi: 10.1097/ACO.0000000000000285.
Kretzschmar M, Kozian A, Baumgardner JE, Schreiber J, Hedenstierna G, Larsson A, Hachenberg T, Schilling T.
Bronchoconstriction induced by inhaled methacholine delays desflurane uptake and elimination in a piglet model.
Respir Physiol Neurobiol. 2016 Jan;220:88-94. doi: 10.1016/j.resp.2015.09.014. Epub 2015 Oct 9.
2015
Kampe S, Weinreich G, Darr C, Eicker K, Stamatis G, Hachenberg T.
The impact of epidural analgesia compared to systemic opioid-based analgesia with regard to length of hospital stay and recovery of bowel function: retrospective evaluation of 1555 patients undergoing thoracotomy.
J Cardiothorac Surg. 2014 Nov 23;9(1):175. doi: 10.1186/s13019-014-0175-8.
Meybohm P,..., Schilling T,..., Zacharowski K; RIPHeart Study Collaborators.
A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery.
N Engl J Med. 2015 Oct 8;373(15):1397-407. doi: 10.1056/NEJMoa1413579.
Schneemilch C, Brinkers M
Der suchtkranke Patient in der Anästhesie – Patienten mit Benzodiazepin-abhängigkeit
Anasthesiol Intensivmed Notfallmed Schmerzther 2015 Jun; 50:416-423
Keilhoff G, Titze M, Esser T, Langnaese K, Ebmeyer U.
Constitutive and functional expression of YB-1 in microglial cells.
Neuroscience. 2015 Jun 20;301:439-453. doi: 10.1016/j.neuroscience.2015.06.023. [Epub ahead of print]
Serpa Neto A, Hemmes SN, Barbas CS,..., Kozian A,..., Schilling T, Schmid W,..., Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ.
Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis.
Anesthesiology. 2015 May 15.
Brinkers M, Pfau G, Voigt A, Schneemilch C.
[Pain therapy in patients with schizoaffective disorder and cancer].
Schmerz. 2015 Apr;29(2):217-22. doi: 10.1007/s00482-014-1505-4. German.
Dewenter H, Brammen D, Walcher F, Thun S.
Comparing representation abilities of semantic standards in the field of Emergency Room Treatment.
Stud Health Technol Inform. 2015;210:973.
Kozian A, Kretzschmar M, Schilling T.:
Thoracic anesthesia in the elderly.
Curr Opin Anaesthesiol. 2015 Feb;28(1):2-9
Kretzschmar M, Hachenberg T.
Thoracic anesthesia.
Curr Opin Anaesthesiol. 2015 Feb;28(1):1.
Kampe S, Weinreich G, Darr C, Stamatis G, Hachenberg T.
Controlled-Release Oxycodone as "Gold Standard" for Postoperative Pain Therapy in Patients Undergoing Video-Assisted Thoracic Surgery or Thoracoscopy: A Retrospective Evaluation of 788 Cases.
Thorac Cardiovasc Surg. 2015 Jan 20.
2014
Serpa Neto A, Hemmes SN, Barbas CS, Beiderlinden M, Fernandez-Bustamante A, Futier E, Hollmann MW, Jaber S, Kozian A, Licker M, Lin WQ, Moine P, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ; PROVE Network investigators.:
Incidence of mortality and morbidity related to postoperative lung injury in patients who have undergone abdominal or thoracic surgery: a systematic review and meta-analysis.
Lancet Respir Med. 2014 Dec;2(12):1007-15. Epub 2014 Nov 13.
Brinkers M, Pfau G, Gerth N, Hachenberg T.
Subsyndromales Delir – Erfahrungen aus der Psychiatrie – Erwartungen für die postoperative Versorgung
Anasthesiol Intensivmed Notfallmed Schmerzther. 2014 Jul;49(7-8):436-41. Epub 2014 Aug 19.
Ahlbrandt J, Brammen D, Majeed RW, Lefering R, Semler SC, Thun S, Walcher F, Röhrig R.:
Balancing the need for big data and patient data privacy - an IT infrastructure for a decentralized emergency care research database.
Stud Health Technol Inform. 2014;205:750-4.
Hachenberg T, Schneemilch C.:
Anesthesia in neurologic and psychiatric diseases: is there a 'best anesthesia' for certain diseases?
Curr Opin Anaesthesiol. 2014 Aug;27(4):394-402.
Hachenberg T.:
Ischämischer Insult – „Time is brain“
Anasthesiol Intensivmed Notfallmed Schmerzther. 2014 Jun;49(6):386-7. Epub 2014 Jul 8.
Wiedemann D, Strang C, Ebmeyer U, Hachenberg T.:
[Management of anaesthesia and intensive care for acute ischemic insult].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2014 Jun;49(6):406-13.
Baumunk D, Strang CM, Kropf S, Schäfer M, Schrader M, Weikert S, Cash H, Breckwoldt J, Miller K, Hachenberg T, Schostak M.:
Impact of Thoracic Epidural Analgesia on Blood Loss in Radical Retropubic Prostatectomy.
Urol Int. 2014 May 17.
Alf Kozian, Thomas Schilling:
Protective Ventilatory Approaches to One-Lung Ventilation: More than Reduction of Tidal Volume.
Current Anesthesiology Reports 2014 Jun, 4(2):150-159
Brinkers M, Gerth N, Pfau G, Hachenberg T.:
Sind die erfolgreich therapierten Patienten die zufriedenen Patienten? Anasthesiol Intensivmed Notfallmed Schmerzther.
2014 Feb;49(2):134-8
Ebmeyer U, Esser T, Keilhoff G.
Low-dose nitroglycerine improves outcome after cardiac arrest in rats.
Resuscitation. 2014 Feb;85(2):276-83
Schilling T, Kozian A.:
Which factors determine prognosis after ventilator-associated pneumothorax in mechanically ventilated patients?
Minerva Anestesiol. 2014 Jan;80(1):3-4.
Bronchopulmonary Complications of Nasogastric tube Placement.
Global Journal of Respiratory Care, 2014, 1, 13-16.
2013
Ebmeyer U, Röse W.:
Entwicklung des Notarztwesens in Deutschland - Ostdeutschland
Anästhesiol Intensivmed Notfallmed Schmerzther 2013; 48(11/12): 730-733
Kretzschmar M, Schilling T, Vogt A, Rothen HU, Borges JB, Hachenberg T,Larsson A, Baumgardner JE, Hedenstierna G:
Multiple inert gas elimination technique by micropore membrane inlet mass spectrometry - a comparison with reference gas chromatography.
J Appl Physiol 2013 doi:10.1152/japplphysiol.00072.2013
Pinkernelle J1, Fansa H, Ebmeyer U, Keilhoff G.:
Prolonged minocycline treatment impairs motor neuronal survival and glial function in organotypic rat spinal cord cultures.
PLoS One. 2013 Aug 13;8(8):e73422.
M Brinkers, A Voigt, G Pfau
Neuropsychiatrische Symptome–Sinnestäuschungen in der Palliativmedizin
Z Palliativmed 2013; 14, pp. 44-46
Schilling T, Kretzschmar M, Hachenberg T, Hedenstierna G, Kozian A:
The immune response to one-lung-ventilation is not affected by repeated alveolar recruitment manoeuvres in pigs.
Minerva Anestesiol 2013; 79:590-603
Strang CM, Hachenberg T:
Aktuelle Strategien zur Minimierung von Blutverlusten bei radikaler Prostatektomie.
Anasthesiol Intensivmed Notfallmed Schmerzther 2013; 48:494-501
Pfau G, Brinkers M, Hachenberg T:
[The Helsinki Declaration for Patient Safety in Anaesthesiology-Post operative care including pain management].
Anasthesiol Intensivmed Notfallmed Schmerzther 2013; 48:474-7
Strang CM, Ebmeyer U, Maripuu E, Hachenberg T, Hedenstierna G.
Improved ventilation-perfusion matching by abdominal insufflation (pneumoperitoneum) with CO2 but not with air.
Minerva Anestesiol 2013; 79:617-25
Keilhoff G, Ebmeyer U, Schild L.
Spontaneous hypothermia is not able to completely counteract cardiac arrest-induced mitochondrial impairment in the rat heart.
Neonatology. 2013;103(2):131-3.
2012
M. Brinkers, G. Pfau, T. Hachenberg
Coenästhesien – eine seltene Schmerzdiagnose bei Patienten mit Tumor: Zwei Kasuistiken (Cenesthesia – A Rare Pain Diagnosis in Palliative Care)
Zeitschrift für Palliativmedizin 2012, vol. 13, no5, pp. 236-239
Langwieler S, Smektala E, Waldburg N, Hachenberg T, Küster D, Schreiber J: [45-year old patient with progressive shortness of breath and “crazy paving”]. Internist (Berl) 2012; 53:1359-63
Schilling T, Hachenberg T: [Pain in thoracic surgery - pathophysiology and treatment options]. Anasthesiol Intensivmed Notfallmed Schmerzther 2012; 47:566-7
M. Brinkers
Depression und Schmerz - Psychopharmaka in der Schmerztherapie
Pharma Focus Schmerztherapie 3. Jahrg. 2012, Nr. 1
Pfau G, Brinkers M, Treuheit T, Kretzschmar M, Senturk M, Hachenberg T: Misoprostol as a Therapeutic Option for Trigeminal Neuralgia in Patients with Multiple Sclerosis. Pain Medicine 2012; 13:1377-8
Hachenberg T, Neu J, Werner S, Wiedemann D, Schaffartzik W: [Quality of anesthesiological expert opinion in medical claims cases]. Anaesthesist 2012; 61:497-502
Meybohm P, Zacharowski K, Cremer J, Roesner J, Kletzin F, Schaelte G, Felzen M, Strouhal U, Reyher C, Heringlake M, Schön J, Brandes I, Bauer M, Knuefermann P, Wittmann M, Hachenberg T, Schilling T, Smul T, Maisch S, Sander M, Moormann T, Boening A, Weigand MA, Laufenberg R, Werner C, Winterhalter M, Treschan T, Stehr SN, Reinhart K, Hasenclever D, et al.: Remote ischaemic preconditioning for heart surgery. The study design for a multi-center randomized double-blinded controlled clinical trial--the RIPHeart-Study. Eur. Heart J. 2012; 33:1423-6
Schneemilch C, Schiltz K, Meinshausen E, Hachenberg T: [Sexual hallucinations and dreams under anesthesia and sedation : medicolegal aspects]. Anaesthesist 2012; 61:234-41
2011
Messelken, M., Schlechtriemen, T., Arntz, H. R., Bohn, A., Bradschetl, G., Brammen, D., & Paffrath, T. (2011). Minimaler Notfalldatensatz MIND3. Notfall+ Rettungsmedizin, 14(8), 647-654.
Mann, V., Brammen, D., Brenck, F., Euler, M., Messelken, M., & Röhrig, R. (2011). Innovative Techniken in der präklinischen Notfallmedizin in Deutschland-Eine Online-Erhebung unter den ärztlichen Leitern Rettungsdienst. Anästh Intensivmed, 11, 824-833.
Schilling T, Kozian A, Senturk M, Huth C, Reinhold A, Hedenstierna G, Hachenberg T: Effects of Volatile and Intravenous Anesthesia on the Alveolar and Systemic Inflammatory Response in Thoracic Surgical Patients. Anesthesiology 2011; 115:65-74
Hachenberg T: [Perioperative prophylaxis and treatment of infections - Current knowledge and outlook]. Anasthesiol Intensivmed Notfallmed Schmerzther 2011; 46:662-3
Schaffartzik W, Hachenberg T, Neu J: [Anaesthetic incidents - Airway management and injuries in anaesthesia - closed claims of the North German Arbitration Board]. Anasthesiol Intensivmed Notfallmed Schmerzther 2011; 46:32-7-quiz38
Hachenberg T: [Anesthesia incidents - treatment and risk of iatrogenic damage]. Anasthesiol Intensivmed Notfallmed Schmerzther 2011; 46:30-1
Strang CM, Freden F, Maripuu E, Ebmeyer U, Hachenberg T, Hedenstierna G: Improved ventilation-perfusion matching with increasing abdominal pressure during CO(2) -pneumoperitoneum in pigs. Acta Anaesthesiologica Scandinavica 2011; 55:887-96
Schott BH, Niklas C, Kaufmann J, Bodammer NC, Machts J, Schütze H, Düzel E
Fiber density between rhinal cortex and activated ventrolateral prefrontal cortex predicts episodic memory performance in humans
PNAS 2011 Vol. 108 No. 13 https://www.pnas.org/doi/full/10.1073/pnas.1013287108
Kozian A, Schilling T, Schütze H, Senturk M, Hachenberg T, Hedenstierna G: Ventilatory protective strategies during thoracic surgery: effects of alveolar recruitment maneuver and low-tidal volume ventilation on lung density distribution. Anesthesiology 2011; 114:1025-35
Brinkers M, Petz T, Hoffmeyer D.
[Psychotropic drugs - The special importance of anticonvulsants and neuroleptics in treatment of patients with chronic pain].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2011 Jan;46(1):20-7.
2010
Hachenberg T: Hachenberg,Anästhesie. Georg Thieme Verlag, 2010
Brinkers M, Petz T, Hoffmeyer D.
[The general importance of antidepressants in treatment of patients with chronic pain].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2010 Nov;45(11-12):712-6.
Brammen, D., Bleicher, W., Branitzki, P., Castelanos, I., Messelken, M., Pollwein, B., & Röhrig, R. (2010). Spezielle Empfehlungen und Anforderungen zur Implementierung von DV-Systemen in der Notfallmedizin. Anaesth Intensivmed, 119-126.
Kozian A, Schilling T, Röcken C, Breitling C, Hachenberg T, Hedenstierna G: Increased alveolar damage after mechanical ventilation in a porcine model of thoracic surgery. J Cardiothorac Vasc Anesth 2010; 24:617-23
Hachenberg T, Sentürk M, Jannasch O, Lippert H: [Postoperative wound infections. Pathophysiology, risk factors and preventive concepts]. Anaesthesist 2010; 59:851-66-quiz867-8
Hachenberg T: [Neurologic diseases--effect of anesthesia in nervous system diseases]. Anasthesiol Intensivmed Notfallmed Schmerzther 2010; 45:316-7
Pfau G, Schilling T, Kozian A, Lux A, Götte A, Huth C, Hachenberg T: Outcome after implantation of cardiac resynchronization/defibrillation systems in patients with congestive heart failure and left bundle-branch block. J Cardiothorac Vasc Anesth 2010; 24:30-6
Schneemilch C: [General anaesthesia for neurological diseases]. Anasthesiol Intensivmed Notfallmed Schmerzther 2010; 45:336-44
Strang CM, Freden F, Maripuu E, Hachenberg T, Hedenstierna G: Ventilation-perfusion distributions and gas exchange during carbon dioxide-pneumoperitoneum in a porcine model. British journal of anaesthesia 2010; 105:691-7